ChIPseek has built-in KEGG databases and user can choose their interested KEGG terms to filter the peaks. In ChIPseek, the KEGG pathways are arranged into tree structure. User can select one or multiple KEGG terms from the annotation tree structures. User may click on the “select“ button to select interested KEGG terms. A new gene list from the KEGG terms can be generated and saved. The gene list, denoted as “selected_acc_1.kegg“ (as indicated in the figure below), can be used as a filter to intersect with other datasets to generate another filtered subset of peaks. A subset of peaks which are near these functionally interested genes can be saved by pressing the “filter & save“ button.
If user has established and saved a gene list through the KEGG trees, this gene list will show up in a separate tab "saved gene lists". Next, user can use the saved gene list as a filter to filter other datasets.